Yes, exposure to PFAS can lead to liver cancer. PFAS chemicals, especially PFOA and PFOS, can bioaccumulate in the liver, disrupting fat metabolism and leading to nonalcoholic fatty liver disease, one of the earliest symptoms of cancer.
The liver is a major target for the accumulation of PFAS because it filters and processes them.
PFAS causes chronic inflammation in the liver cells and induce oxidative stress, damaging DNA, and interfering with nuclear receptors, which promote liver tumor development.
Research suggests that PFAS plays multiple roles in the development of liver cancer. NAFLD, which can progress to liver cancer over time, is caused by metabolic disruption by PFAS. Additionally, PFAS increases reactive oxygen species that directly damage liver cells and DNA, and promote persistent inflammatory responses that create cancer-promoting environments in liver cells.
Rodent studies consistently show that PFAS exposure causes liver tumors. According to human epidemiological studies, PFAS exposure increases the risk of liver disease and cancer, especially among workers exposed to high levels of PFAS or communities living near contaminated sites. PFAS exposure is associated with a higher risk of liver cancer in certain groups, especially men, although some large population studies have found mixed results.
The evidence is particularly strong for PFOA and PFOS, the most studied PFAS compounds, though research suggests other PFAS chemicals may pose similar liver cancer risks. Early detection and intervention are critical since PFAS exposure leads to progressive liver disease, including fatty liver disease and possibly cancer.
We have over 35 years of experience dealing with toxic exposure cases, and we will evaluate your case to see if you qualify for financial compensation for liver cancer caused by PFAS exposure from military bases. Consultations are mainly conducted over the phone and are straightforward. Those who qualify will be matched with experienced, specialized attorneys who have experience litigating PFAS cases.