Perfluoroalkyl and polyfluoroalkyl substances (PFAS) have been associated with blood cancers in men.
Additionally, multiple studies have found a connection between PFAS chemicals and the bone marrow, which is where a type of blood cancer called multiple myeloma typically begins. The following studies have found that PFAS prefer the bone marrow as a sink (site of accumulation) and that the chemicals can change the bone’s microenvironment:
- Researchers studied the distribution of perfluorooctane sulfonate (PFOS), a type of PFAS, in mice. They found that the highest levels of PFOS were detected in blood, bone marrow, and three other organs.
- In a study of human bones, PFAS was detected in every bone and bone marrow sample from an anonymous bone bank. Another type of PFAS, called perfluorooctanoic acid (PFOA), was more concentrated in the bone marrow than in the spongy bone tissue. A study published in Environment International also found that PFOA was the predominant PFAS compound in human bone tissue.
- A study of PFAS effects on bone marrow in mice found that a six-carbon PFAS compound, PFHxS, had the highest concentration in the bone. Researchers have found that PFAS can potentially disrupt the balance between osteoblasts and adipocytes, altering the bone marrow microenvironment. These changes can potentially promote bone resorption, decrease bone quality, and support the survival of myeloma cells and tumors.
We can evaluate your eligibility to file claims for PFAS-associated multiple myeloma
If you have been diagnosed with multiple myeloma and are wondering if PFAS exposure is connected to your condition, you may schedule a consultation with Atraxia Law to discuss your case and eligibility. Upon checking your documents, we can connect you with a toxic exposure attorney who can file your PFAS exposure claim for multiple myeloma. Additionally, we highly encourage you to also file a VA claim for multiple myeloma if you are a military veteran.